CHEMICAL RESEARCH IN TOXICOLOGY

Toxicology is the study involving the study of the threats chemical substances pose to living organisms. It is an overlap of biology, pharmacology, medicine, and chemistry that practices the diagnosing and treating the adverse effects of exposure of such toxins and toxicity.

It determines the assessment of the risk posed to humans, animals, and the environment on being exposed to industrial chemicals, biocides, plant protection products, medical drugs, etc. Chemical Research in Toxicology is a monthly American Chemical Society published peer-review journal since 1988. There are many few R&D companies follows all the safety norms and one of them is lizardlabs.to who also sells different chemical products online after great research.

Polychlorinated biphenyls and their correlation with oxidative stress – The recent journal published by the American Chemical Society was on July 17th, 2020, regarding the Critical Review of Polychlorinated Biphenyls Metabolism, Metabolites, and the correlation they have with Oxidative Stress. Polychlorinated biphenyls are organic pollutants that were banned in the previous century itself.

However, they still are unambiguously present all over the ecosystem due to their bioaccumulative potency and persistence against biological and environmental degradation. Despite there not being any permission for PCB’s commercial production, they have been continuously released into the environment through e-wastes or by-products of industrial supplies. PCBs also take the longest time to decompose due to their varying size and composition. A variety of adverse health effects are being caused by PCB’s and it is quite evident.

Exposure to a large amount of PCB can cause cancer. There are several noncancer health effects on animals on the immune and reproductive systems. The review has the aim of providing a critical summary of PCBs metabolism, PCBs parents, and daughter metabolite- induced oxidative stress. Its primary focus is to perform research associated with PCB metabolite – induced oxidative stress as well as to figure out the connection between parent PCBs and downstream metabolites.

Analysis of the biogenesis, toxicity, and control of microcystins – Another journal published on July 2nd, 2020, was about Biogenesis, Toxicity, Analysis, and Control. Some freshwater blue-green algae produce a class of toxins named Microcystins. The amount of toxin absorbed may affect the liver with an outcome of minor to widespread damage.

They are formed by cyanobacteria and are known for their association with algal blooms, which poses a significant threat to the drinking water quality and ecosystems. On staying in contact with cyanobacteria, allergic reactions like asthma, rashes, eye irritation, and blisters around the nose and mouth make occur. There are a wide number of symptoms of the existence of cyanobacteria in the human body, including nausea, mouth ulcers, blistering lips, muscle aches, vomiting, abdominal pain, stomach cramps, diarrhea, dizziness, etc. They raise an environmental concern.

Hence an outline is made in the journal on microcystins genesis, toxicity, and analytical methods for their quantitative determination. The journal discusses various analytical ways to detect, separate, and quantify microcystins, including the quantitative real-time polymerase chain reaction. Since there is a great necessity of controlling microcystins in water, the water treatment and mechanisms of abiotic transformation and microbial degradation have also been discussed here.

The peer-reviewed journals continue publishing articles every month based on their chemical research on toxicology.

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